A viable therapy is needed to overcome the deadlock of the incurable chronic hepatitis B (CHB).The prolonged existence of covalently closed circular DNA (cccDNA) and integrated HBV DNA in the nucleus of hepatocytes is the root cause of CHB.As a result, it is critical to successfully suppress HBV DNA replication and eliminate cccDNA.RNA interference
Purpose: To describe the ophthalmic symptoms and histopathological findings in a human case of Eastern equine encephalitis (EEE).Observations: The patient was a septuagenarian male whose presentation and clinical course were thought to be most consistent with viral meningoencephalitis.ELISA suggested recent infection with EEE virus.Microscopic anal
Risk factors for psychiatric disorders have traditionally been classified as genetic or environmental.Risk (candidate) genes, although typically possessing small effects, represent a clear starting point to elucidate downstream cellular/molecular pathways of disease.Environmental effects, Laundry - Bags and Liners especially during development, can
Abstract This paper critically assesses the complex interplay between urban transitions of digitisation and sustainability.Building on a mixed-method research design, we unpack the challenges of decarbonising digital infrastructure while attending to urban sustainability goals in a land- and water-scarce Backpacks country facing significant physica